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Wednesday, November 20, 2013
| Time | Event | |
| 13:00 - 14:00 | Welcome in Toulouse Mercure Hotel - Badges and abstract books delivery. | |
| 14:00 - 14:15 | Welcom address - Welcome | |
| 14:15 - 14:35 | Role of DNA polymerase eta in somatic hypermutation - Fumio Hanaoka | |
| 14:35 - 14:55 | Novel functions of the so-called “TLS” DNA polymerases DNA polymerases for the regulation of the replication program in human cells - Christophe Cazaux | |
| 14:55 - 15:15 | Impact of replication stress on S-phase checkpoint and common fragile site instability - Michèle Debatisse | |
| 15:15 - 15:35 | Low-dose stress responses - Fuyuki Ishikawa | |
| 15:35 - 16:00 | Role of TRF2 in oncogenesis - Eric Gilson | |
| 16:00 - 16:30 | Coffee break | |
| 16:30 - 16:50 | DNA replication: from origins to DNA damage and cell identity - Marcel Méchali | |
| 16:50 - 17:10 | Telomere length influences cancer cell differentiation in vivo - Hiroyuki Seimiya | |
| 17:10 - 17:30 | Repair of the shortest telomeres delays replicative senescence - Vincent Géli | |
| 17:30 - 17:50 | Integrated genomic analysis of hepatocellular carcinoma - Hiroyuki Aburatani | |
| 17:50 - 18:10 | Transcription/replication interference as a source of genomic instability and cancer - Philippe Pasero | |
| 18:10 - 18:25 | Tissue specific replication defects and their different outcome in MCM8 and MCM9 knock out mice - Malik Lutzmann (short talk 1) | |
| 19:30 - 21:30 | Dinner |
Thursday, November 21, 2013
| Time | Event | |
| 08:30 - 08:50 | ASXL1 mutations induce an MSD-like disease in mice via derepression of HoxA9 and miR125a - Toshio Kitamura | |
| 08:50 - 09:10 | The H3.3 histone chaperone HIRA primes chromatin for transcription recovery after DNA damage - Geneviève Almouzni | |
| 09:10 - 09:30 | Genomic imprinting in mammals: ‘imprinting control regions’ mediate mono-allelic expression at endogenous and ectopic gene loci - Robert Feil | |
| 09:30 - 09:50 | Ubiquitylation/deubiquitylation circuit of histone H3 at K23 couples maintenance DNA methylation with DNA - Makoto Nakanishi | |
| 09:50 - 10:10 | A small molecule, agonist of aldosterone, sensitizes cancer cells to platinum derived treatment through the degradation of the XPB helicase of TFIIH - Frédéric Coin | |
| 10:15 - 10:45 | Coffee break | |
| 10:45 - 11:05 | When splicing meets splicing - Annick Harel-Bellan | |
| 11:05 - 11:25 | Polycomb proteins in Drosophila development and cancer - Giacomo Cavalli | |
| 11:25 - 11:45 | Breast cancer risks in germline BRCA1 mutations carrier women - Jean Feunteun | |
| 11:45 - 12:00 | Molecular links between microenvironmental signals and epigenetic reprogramming processes via long non-coding RNA in glioblastoma - Yutaka Kondo (short talk 2) | |
| 12:00 - 12:15 | Tumor Suppressor FOXP3 Orchestrates H4K16ac and H3K4me3 for Target Gene Activation in Breast Cancer Cells - Hiroto Katoh (short talk 3) | |
| 12:30 - 13:45 | Lunch | |
| 14:00 - 14:20 | What is the Warburg effect ? Next-generation proteomics uncovers the secret of cancer. - Keiichi Nakayama | |
| 14:20 - 14:40 | Characterization of a Mink1-Prickle pathway implicated in cancer cell migration - Avais Daulat | |
| 14:40 - 15:00 | Coordinated Controls of checkpoints and metabolism by the transcription factor E4F1: Toward novel synthetic lethal approaches to cancer vulnerabilities? - Claude Sardet | |
| 15:00 - 15:15 | Hypoxia and nutrient starvation induce tumor aggressiveness - Tsuyoshi Osawa (short talk 4) | |
| 15:15 - 15:30 | Elucidation of the roles of membrane lipids in the progression of epithelial-mesenchymal transition - Junichi Ikenouchi (short talk 5) | |
| 15:30 - 16:00 | Coffee break | |
| 16:00 - 16:20 | Molecular mechanisms of osteoclastogenic signal - Jun-Ichiro Inoue | |
| 16:20 - 16:40 | Study of mechanical stress and tumor cell proliferation in multi-cellular tumor spheroid - Valérie Lobjois | |
| 16:40 - 17:00 | Loss of E-cadherin in the liver leads to sclerosing cholangitis and promotes tumorigenesis in mice - Shin Maeda | |
| 17:00 - 17:20 | Cyclin A2: a novel player in cell-cell and cell-niche interactions - Jean-Marie Blanchard | |
| 17:20 - 17:40 | Cullin3 E3 ubiquitin ligase-based angiogenic regulation - Shigeki Higahsiyama | |
| 17:40 - 17:55 | Biochemical and biophysical analysis for the H. pylori CagA-SHP2 oncoprotein interaction - Takeru Hayashi (short talk 6) | |
| 18:30 - 19:30 | Reception by the Mayor of Toulouse - Salles des Illustres - Capitole - Salles des Illustres - Capitole | |
| 19:30 - 21:00 | A guided walk in Toulouse by night - A walk in Toulouse | |
| 21:00 - 23:00 | Dinner |
Friday, November 22, 2013
| Time | Event | |
| 08:30 - 08:50 | HTLV-1 bZIP factor determines cell tropism - Masao Matsuoka | |
| 08:50 - 09:10 | Cell polarity, cell signaling and cancer - Jean-Paul Borg | |
| 09:10 - 09:30 | Mechanisms determining subcellular localization of the oncogenic protein tyosinase phosphatase SHP2 - Masanori Hatakeyama | |
| 09:30 - 09:45 | TTF-1/NKX2-1-induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma - Tomoya Yamaguchi (short talk 7) | |
| 09:45 - 10:00 | Novel functions of Wnt signaling pathways in mitotic progression. - Koji Kikuchi (short talk 8) | |
| 10:00 - 10:30 | Coffee break | |
| 10:30 - 10:50 | Mechanisms of development in childhood cancers, translational perspectives - Olivier Delatre | |
| 10:50 - 11:05 | Oncogenic role of the retina-specific transcription factor NRL in metastatic medulloblastoma - Célio Pouponnot (short talk 9) | |
| 11:05 - 11:25 | Specific roles for BRAF and CRAF in NRAS-induced mouse melanoma - Alain Eychène | |
| 11:25 - 11:40 | Contribution of Keap1-Nrf2 pathway to metabolic reprogramming and cell proliferation - Hozumi Motohashi (short talk 10) | |
| 12:00 - 13:30 | Lunch | |
| 14:00 - 20:00 | Oncopole tour, Carcassonne medieval city…and red wine ! - Oncopole tour, Carcassonne medieval city…and red wine ! | |
| 21:00 - 23:00 | Dinner |
Saturday, November 23, 2013
| Time | Event | |
| 08:30 - 08:50 | CD44s-xCT axis is a therapeutic target for cancer stem cells - Hideyuki Saya | |
| 08:50 - 09:10 | Function of thrombopoietin receptor (MPL) mutations in hematological myeloid malignancies - William Vainchenker or Isabelle Plo | |
| 09:10 - 09:30 | The calcineurin/NFAT pathway in leukemia and breast cancer models - Christine Tran Quang | |
| 09:30 - 09:50 | Genetic analysis of Down Syndrome-related myeloid neoplasms - Seishi Ogawa | |
| 09:50 - 10:10 | Tumor HEVs: specialized blood vessels which contribute to the fight against cancer - Jean-Philippe Girard | |
| 10:15 - 10:45 | Coffee break | |
| 10:45 - 11:05 | Leukemic gene network: from genetic interaction to in vivo function - Takuro Nakamura | |
| 11:05 - 11:25 | Activation of distinct oncogenic signaling pathways in human mammary epithelial cells results in fully different cascades of genetic and epigenetic modifications - Charles Theillet | |
| 11:25 - 11:40 | Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence - Shoichiro Takeishi (short talk 11) | |
| 11:40 - 12:00 | Small nucleolar RNAs and long non coding RNAs: new players in hematological cancers - Pierre Brousset | |
| 12:00 - 12:20 | PML, an essential contributor of APL response to targeted therapies - Hugues de Thé | |
| 12:30 - 13:00 | Conclusions - End of meeting - End talk |
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